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Endo agrees settlement on US charges on opioid crisis

US officials announced Thursday an agreement with Endo Health Solutions (EHSI) to settle civil and criminal claims over the mislabeling of its pain reliever drug Opana, which has contributed to the opioid epidemic.

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Publicis settles opioid case with US states for $350 mn

Publicis Health will pay $350 million to settle charges from US states that its "predatory and deceptive marketing strategies" worsened the opioid epidemic, New York's top prosecutor said Thursday.

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Epidemic

In epidemiology, an epidemic (επι (epi)- meaning "upon or above" and δεμος (demos)- meaning "people"), occurs when new cases of a certain disease, in a given human population, and during a given period, substantially exceed what is expected based on recent experience.:354 Epidemiologists often consider the term outbreak to be synonymous to epidemic, but the general public typically perceives outbreaks to be more local and less serious than epidemics:55, 354

An epidemic may be restricted to one locale, however if it spreads to other countries or continents and affects a substantial number of people, it may be termed a pandemic.:55 The declaration of an epidemic usually requires a good understanding of a baseline rate of incidence; epidemics for certain diseases, such as influenza, are defined as reaching some defined increase in incidence above this baseline. A few cases of a very rare disease may be classified as an epidemic, while many cases of a common disease (such as the common cold) would not.

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