Medical research

Psoriasis: Towards a novel therapeutic approach

Psoriasis is a frequent skin inflammatory disorder affecting 3% of the population. Psoriasis is characterized by hyperproliferation and defect of epidermal differentiation, leading to the scaly appearance of the skin. Psoriatic ...

Medical research

3-D human epidermal equivalent created using math

Scientists have successfully constructed a three-dimensional human epidermis based on predictions made by their mathematical model of epidermal homeostasis, providing a new tool for basic research and drug development.

Medical research

Researchers report epidermal cell differentiation findings

To ensure the barrier function of the skin, mutual regulation of connections between epidermal cells and a receptor for growth factors is necessary. These findings can help to reduce the effects of inflammatory skin diseases ...

Medical research

Collagen controlling the thickness and juvenile state of skin

Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.

Diseases, Conditions, Syndromes

Vitiligo can mask symptoms of acanthosis nigricans

(HealthDay)—Vitiligo can mask symptoms of acanthosis nigricans (AN), according to a case report published in the November issue of the International Journal of Dermatology.