Medical research

Epigenetic clock predicts life expectancy

UCLA geneticist Steve Horvath led a team of 65 scientists in seven countries to record age-related changes to human DNA, calculate biological age and estimate a person's lifespan. A higher biological age—regardless of chronological ...

Medical research

Lifetime stress accelerates epigenetic aging

An important risk factor for accelerated aging and age-related diseases is excessive or chronic stress. Scientists at the Max Planck Institute of Psychiatry in Munich have now found how psychological stress, which accumulates ...

HIV & AIDS

Research links HIV to age-accelerating cellular changes

People undergoing treatment for HIV-1 have an increased risk for earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive disease. But is it because of ...

Genetics

Secrets of youth, based on prevention

Metabolites found in our blood are linked to ageing and can signpost the risk of developing age-related diseases. This may help avoid such risks and reduce the rate at which we age biologically.

Genetics

Twins studies to identify the molecular cause of ageing

What makes us age biologically? We have always been intrigued by this question. Yet, it remains a fundamental research challenge. Now, the EU-funded project, EurHEALTHAgeing, aims to draw together studies of early development ...

Oncology & Cancer

Linking risk factors and disease origins in breast cancer

Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe ...

Alzheimer's disease & dementia

Epigenetic markers shows promise in Alzheimer's disease

Increasing evidence suggests that epigenetic regulation is associated with the pathogenesis of Alzheimer's disease (AD) and targeting it may one day lead to novel diagnostic and therapeutic strategies, research suggests.

Medical research

Reversing blood and freshening it up

The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice ...

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