Published in Nature Microbiology, a study in mice finds that the microbial basis for urinary tract infections can include localized epigenetic alterations that make additional infections more likely.
A graduate student's curiosity has uncovered a previously unknown link between two important hallmarks of cancer: chromosomal instability and epigenetic alterations.
Jun 7, 2023
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Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues. However, deregulation of the immune system can lead to uncontrolled inflammation and produce lesions instead. ...
Apr 27, 2023
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Investigators have identified previously unknown sets of epigenetic changes in pediatric brain tumors, which could serve as novel therapeutic targets and provide alternative treatment options for patients, according to a ...
Dec 6, 2022
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Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates.
Dec 6, 2022
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Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.
Jun 9, 2022
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Researchers have identified a molecular mechanism that drives the progression of uveal melanoma (UM), an often lethal eye cancer in adults.
Sep 13, 2021
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Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...
Aug 4, 2021
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A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...
Mar 5, 2021
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A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The ...
Nov 12, 2020
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