Oncology & Cancer

Exposing cancer's metabolic addictions

Cancerous tumors are classified primarily based on their tissue of origin. However, the sequencing of the human genome and the development of powerful and affordable DNA sequencing technologies has ushered in a new era of ...

Genetics

Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off", and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

Psychology & Psychiatry

Novel autism mouse model based on an epigenetic gene developed

The causes of autism spectrum disorder (ASD) are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced. In a study published January 17, 2019 in Translational Psychiatry, researchers ...

Neuroscience

Nature versus nurture and addiction

The progressive understanding of addiction as a disease rather than a choice has opened the door to better treatment and research, but there are aspects of addiction that make it uniquely difficult to treat.

Immunology

Asthmatics show DNA changes in immune cells

Children with asthma have epigenetic DNA changes in certain cells of their immune system, a major international study involving researchers at Karolinska Institutet shows. The finding, which is presented in The Lancet Respiratory ...

Genetics

Immune diseases inflict identical twins differently

Any parent with identical twins knows their two children are actually remarkably different. Identical twins are genetically identical, but they are not identical in gene expressions, a difference attributable to epigenetics. ...

Oncology & Cancer

Anti-myeloma agent opens for new treatment strategy

The tumour form multiple myeloma is very challenging to treat and is still considered incurable. In a recently published study in the scientific journal Oncotarget, researchers at Uppsala University show how inhibition of ...

Diseases, Conditions, Syndromes

Epigenetic drugs show promise as antivirals

Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a study reported in a recent issue of the journal mBio. The study demonstrated that histone methyltransferases EZH2/1 ...

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