News tagged with epigenome

Epigenome

Epigenome is equivalent to genome in epigenetics. Epigenetics is one of the current topics in cancer research drawing active research. Human tumors undergo a major disruption of DNA methylation and histone modification patterns. The aberrant epigenetic landscape of the cancer cell is characterized by a massive genomic hypomethylation, CpG island promoter hypermethylation of tumor suppressor genes, an altered histone code for critical genes and a global loss of monoacetylated and trimethylated histone H4.

Much of the subject matter is not yet fully understood. Some people have suggested a Human Epigenome Project.[citation needed]

This text uses material from Wikipedia, licensed under CC BY-SA

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