Oncology & Cancer

Origins of glioma brain cancer found to be in the epigenome

While cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at Dana-Farber and the Broad Institute of MIT and Harvard have found that gliomas—incurable brain ...

Psychology & Psychiatry

Depression during pregnancy linked to placental gene modifications

Episodes of maternal stress or depression during pregnancy are associated with chemical modifications to placental genes, according to a study by researchers from the National Institutes of Health. The modifications involve ...

Genetics

Researchers unlock the secrets of liver regeneration

In a recent study published in the journal Developmental Cell, NYU Abu Dhabi researchers have reported a new way in which the liver is primed to regenerate itself. They found that by stripping parts of the epigenome, which ...

page 1 from 4

Epigenome

Epigenome is equivalent to genome in epigenetics. Epigenetics is one of the current topics in cancer research drawing active research. Human tumors undergo a major disruption of DNA methylation and histone modification patterns. The aberrant epigenetic landscape of the cancer cell is characterized by a massive genomic hypomethylation, CpG island promoter hypermethylation of tumor suppressor genes, an altered histone code for critical genes and a global loss of monoacetylated and trimethylated histone H4.

Much of the subject matter is not yet fully understood. Some people have suggested a Human Epigenome Project.[citation needed]

This text uses material from Wikipedia, licensed under CC BY-SA