Medical research

Does dietary restriction protect against age-related leaky gut?

Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition ...

Medical research

A new defender for your sense of smell

New research from the Monell Center increases understanding of a mysterious sensory cell located in the olfactory epithelium, the patch of nasal tissue that contains odor-detecting olfactory receptor cells. The findings suggest ...

Cancer

Colorectal cancer: Tipping the scales

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...

Neuroscience

Scientists uncover new details in how sense of smell develops

Dogs, known for their extraordinarily keen senses of smell, can be trained to use their sensitive sniffers to find drugs, bombs, bed bugs, missing hikers and even cancer. Among dogs and other animals that rely on smell, at ...

Medical research

Stem-cell niche for 10 billion colon cells a day

Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible ...

Immunology

Mouse study adds to evidence linking gut bacteria and obesity

A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome—a "garden" of bacterial, viral and fungal genes—plays a substantial role in the development ...

Medical research

When the nose doesn't know: Can loss of smell be repaired?

Researchers at Tufts University School of Medicine, led by Dr. James E. Schwob, are examining the behavior of adult stem cells within the context of aging and, specifically, the sense of smell. As part of the normal aging ...

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. In Greek "Epi" means, "on, upon," and "Theli" meaning "tissue." Epithelial layers are avascular, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane.[unreliable source?] Epithelia can also be organized into clusters of cells that function as exocrine and endocrine glands. Exocrine and endocrine epithelial cells are highly vascular.

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