Immunology

Unveiling a novel immune response in the intestinal epithelium

Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism ...

Addiction

Understanding mechanisms of alcohol-associated bowel disease

Alcohol consumption is a significant risk factor for gastrointestinal diseases, including cancer. Alcohol can damage the gastrointestinal tract in several ways. It can promote an impairment of several intestinal barrier functions, ...

Gastroenterology

Study sheds light on how IBD can develop

Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune ...

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. In Greek "Epi" means, "on, upon," and "Theli" meaning "tissue." Epithelial layers are avascular, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane.[unreliable source?] Epithelia can also be organized into clusters of cells that function as exocrine and endocrine glands. Exocrine and endocrine epithelial cells are highly vascular.

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