Diseases, Conditions, Syndromes

Bone abnormalities in systemic autoimmune disease

An article published in Experimental Biology and Medicine details abnormalities in bone pathology that occur in systemic autoimmune disease. The study, led by Dr. Yasuhiro Kon, Professor in the Department of Basic Veterinary ...

Obstetrics & gynaecology

Placental function linked to brain injuries associated with autism

Allopregnanolone (ALLO), a hormone made by the placenta late in pregnancy, is such a potent neurosteroid that disrupting its steady supply to the developing fetus can leave it vulnerable to brain injuries associated with ...

Medications

New drug mimics benefits of ketamine for depression

A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows.

Diseases, Conditions, Syndromes

New research insights hold promise for kids with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects. Eplerenone, a heart failure drug, is used in older patients to treat ...

Medications

Opioid crisis roadmap overlooks gender

Women's Health Research at Yale (WHRY) is calling on a government committee to revise its report on a coordinated response to the opioid epidemic so that it reflects the unique needs of women.

Immunology

Pathway to resolve allergic asthma is discovered

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible ...

Neuroscience

Realizing the potential of gene therapy for neurological disorders

Promising findings from preclinical animal studies show the potential of gene therapy for treating incurable neurological disorders. In new research presented today, scientists successfully used gene therapy to slow the progression ...

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