Alzheimer's disease & dementia

Experimental Alzheimer's drug improves memory in mice

An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...

Neuroscience

New approach to treating chronic itch

Researchers at the University of Zurich have discovered a new approach to suppressing itch by targeting two receptors in the spinal cord with the right experimental drug. In a series of experiments in mice and dogs, they ...

Ophthalmology

Drug shows promise against vision-robbing disease in seniors

An experimental drug is showing promise against an untreatable eye disease that blinds older adults—and intriguingly, it seems to work in patients who carry a particular gene flaw that fuels the damage to their vision.

Oncology & Cancer

Researchers 'turn off' most notorious cancer-causing protein

It's known as the most common cancer-causing protein, directly responsible for 30 per cent of all cancers and indirectly involved in virtually all cancers. For over 30 years, scientists have failed to successfully target ...

Overweight & Obesity

Can a new drug brown the fat and trim the obese person?

New research has found that a variant of a drug used to treat pulmonary arterial hypertension prompts weight loss in obese mice. Among mice fed a high-fat diet, those who did not get the medication became obese while medicated ...

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