Medical research

Targeting cancers' surroundings to prevent or limit metastasis

Cancer depends on blood. Just like the rest of the body, tumors need blood vessels to supply them with nutrients and oxygen to grow. But cancer uses these vessels in another way as well—to spread to other parts of the body.

Diseases, Conditions, Syndromes

Bone abnormalities in systemic autoimmune disease

An article published in Experimental Biology and Medicine details abnormalities in bone pathology that occur in systemic autoimmune disease. The study, led by Dr. Yasuhiro Kon, Professor in the Department of Basic Veterinary ...

Obstetrics & gynaecology

Placental function linked to brain injuries associated with autism

Allopregnanolone (ALLO), a hormone made by the placenta late in pregnancy, is such a potent neurosteroid that disrupting its steady supply to the developing fetus can leave it vulnerable to brain injuries associated with ...

Medications

New drug mimics benefits of ketamine for depression

A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows.

Diseases, Conditions, Syndromes

New research insights hold promise for kids with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects. Eplerenone, a heart failure drug, is used in older patients to treat ...

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