Overweight and obesity pose significant health risks, including an increased likelihood of developing diabetes, cardiovascular disease, and cancer. Researchers are seeking practical ways to promote the oxidation of lipids, ...
May 9, 2023
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Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.
Feb 13, 2023
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Post-surgical radiotherapy and temozolomide, a chemotherapeutic drug, targeting post-cell division is the current standard of care for glioblastoma (GBM)—the most prevalent and lethal primary tumor of the central nervous ...
Jan 18, 2023
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Cancer is a complex disease and although billions of dollars have been spent on finding safe and effective therapeutics for it, there is still scope for significant development. Researchers have targeted a variety of biological ...
Jan 6, 2023
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The microbes that help break down food actually tell the gut how to do its job better, according to a new study in mice at Duke.
May 13, 2022
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A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)—cells that support heart muscle contraction, generated in the ...
Apr 7, 2022
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Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell ...
Dec 21, 2021
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A form of cell communication called hedgehog signaling is vital for embryonic development in mammals. But aberrantly activated hedgehog signaling in multiple cancer types—including breast cancer—promotes tumor invasion, ...
Aug 16, 2021
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Adipose tissue is essential for the establishment and maintenance of functional metabolism, secreting large amounts of adipokines that affect fatty acid oxidation in skeletal muscle and liver.
Jul 7, 2021
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Fatty acids are formed when fat breaks down during digestion. While many of the body's organs use glucose as their primary energy source, the heart derives most of its required energy (over 70%) from the oxidation of fatty ...
Jun 29, 2021
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