Immunology

Review discusses metabolic reprogramming of T cells

When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...

Oncology & Cancer

Scientists enhance cell-based therapy to destroy solid tumors

Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells—an approach known as "cell-based therapy," which uses specially designed T cells to fight ...

Medical research

A step toward treating chemotherapy-resistant prostate cancer

Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications—cisplatin. Now, researchers reporting in ACS Central Science have developed the first ...

Genetics

A new player unveiled for lipid oxidation

Overweight and obesity pose significant health risks, including an increased likelihood of developing diabetes, cardiovascular disease, and cancer. Researchers are seeking practical ways to promote the oxidation of lipids, ...

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