Medical research

Fighting sickle cell disease using a medication for type 2 diabetes

Sickle cell disease and the blood disorder beta thalassemia affect more than 180,000 Americans and millions more worldwide. Both diseases can be made milder or even cured by increasing fetal hemoglobin (HbF) levels, but current ...

Medical research

Forcing chromosomes into loops may switch off sickle cell disease

Scientists have altered key biological events in red blood cells, causing the cells to produce a form of hemoglobin normally absent after the newborn period. Because this hemoglobin is not affected by the inherited gene mutation ...

Diabetes

Fetal hemoglobin glycation may reflect hyperglycemia in utero

(HealthDay)—Glycation of the α-chain (Glα) in fetal hemoglobin is higher in neonates from women with gestational diabetes mellitus and may reflect hyperglycemia exposure in utero, according to a study published online ...

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