Alzheimer's disease (AD) is a debilitating incurable disease that affects millions of patients worldwide. Deposits of amyloid beta (Aβ) amyloid in the brain is key to AD pathology at early stages. Apolipoprotein E (apoE) ...
Dec 7, 2023
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For more than 30 years, scientists have been trying to unravel the mystery of how a key biological molecule self assembles into a rogue protein-like substance known as amyloid, which is thought to play a role in the development ...
Feb 24, 2022
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Scientists have for the first time identified the structure of a protein fiber linked to early-onset type 2 diabetes.
Sep 14, 2020
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A Virginia Tech research team has discovered insights into the stabilizing forces of amyloid fibrils that are associated with Alzheimer's disease and type 2 diabetes.
Jun 26, 2018
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Depression may increase the risk for atrial fibrillation, the most common heart rhythm disorder that can lead to blood clot formation and stroke, according to preliminary research presented at the American Heart Association's ...
Mar 22, 2018
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Medical researchers at the Ludwig Maximilian University of Munich have discovered why a new class of anticoagulants designed to reduce the risk of strokes can—in rare cases—increase the incidence of heart attacks.
Dec 6, 2016
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Using specialized CT scans of a healthy heart and one with heart disease, a team of Johns Hopkins cardiologists and biomedical engineers say they've created computer models of the "shape" of blood flow through the heart's ...
Nov 2, 2016
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The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is ...
Feb 17, 2015
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Computing resources at the U.S. Department of Energy's (DOE) Argonne National Laboratory have helped researchers better grasp how proteins misfold to create the tissue-damaging structures that lead to type 2 diabetes. The ...
Dec 20, 2013
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(Medical Xpress)—Australians are being warned of a higher risk of stroke caused by the nation's most common heart rhythm disorder, atrial fibrillation.
Feb 11, 2013
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