Medical research

Engineered miniature kidneys come of age

In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, liver, intestine, ...

Cardiology

Babies born with broken hearts

More than 35,000 babies are born with life-threatening congenital heart defects every year in the United States. Fetal single ventricle defects can be identified with echocardiograms. In the first months of life, surgeries ...

Arthritis & Rheumatism

Scientists uncover why knee joint injury leads to osteoarthritis

Knee joint injuries are typically related to sports, such as football, rugby or ice hockey, but people often do not know that such injuries may lead to joint inflammation and post-traumatic osteoarthritis. In advanced post-traumatic ...

Cancer

Immune-engineered device targets chemo-resistant lymphoma

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels ...

Medical research

Gut response to fluid flow

Flow of fluids through the gut, such as milk from an infant's diet, generates a shear stress on cells lining the intestine. Ken Lau, Ph.D., and colleagues have demonstrated that microvilli – finger-like membrane protrusions ...

Neuroscience

How whip-like cell appendages promote bodily fluid flow

Researchers at Nagoya University have identified a molecule that enables cell appendages called cilia to beat in a coordinated way to drive the flow of fluid around the brain; this prevents the accumulation of this fluid, ...

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