Neuroscience

New chemical reagent turns mouse brain transparent

Japanese researchers at RIKEN have developed a ground-breaking new aqueous reagent which literally turns biological tissue transparent. Experiments using fluorescence microscopy on samples treated with the reagent, published ...

Medical research

Alternate ending -- living on without telomerase

Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes.

Medical research

Nanobody-drug conjugates hijack the human vitamin B12 uptake route

A major challenge in cancer therapy is selectively targeting cancer cells over healthy ones. A recent study by the Locher group (IMBB) describes the development of camelid single-domain antibodies (nanobodies) that selectively ...

Neuroscience

Sugar solution makes tissues see-through

Japanese researchers have developed a new sugar and water-based solution that turns tissues transparent in just three days, without disrupting the shape and chemical nature of the samples. Combined with fluorescence microscopy, ...

Neuroscience

Better hearing with optical cochlear implants

Cochlear implants enable people with profound hearing impairment to gain a great deal in terms of quality of life, including understanding spoken words and developing normal speech. However, background noises are problematic; ...

Medical research

Detailed picture of how myoV 'walks' along actin tracks

A new study in the Journal of General Physiology uses state-of-the-art fluorescence microscopy to provide a striking 3-D picture of how class V myosins (myoV) "walk" along their actin track.

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Fluorescence microscope

A fluorescence microscope (colloquially synonymous with epifluorescent microscope) is a light microscope used to study properties of organic or inorganic substances using the phenomena of fluorescence and phosphorescence instead of, or in addition to, reflection and absorption.

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