Neuroscience

Head-mounted microscope reaches deeper into mouse brains

Researchers have developed a miniature microscope that is designed for high-resolution 3D images inside the brains of living mice. By imaging deeper into the brain than previously possible with miniature widefield microscopes, ...

Medical research

Nanobody-drug conjugates hijack the human vitamin B12 uptake route

A major challenge in cancer therapy is selectively targeting cancer cells over healthy ones. A recent study by the Locher group (IMBB) describes the development of camelid single-domain antibodies (nanobodies) that selectively ...

Genetics

New method for genetic analysis of resting human immune cells

CD4+ T cells are important parts of the immune system and play a key role in defending the body against pathogens. As they possess a great variety of defense mechanisms against HIV in their resting state, they are infected ...

Inflammatory disorders

Analyzing kidney stones using geology and cancer screening techniques

Up to 15% of people will experience kidney stones, and for 50% of those that do, they will recur. It is therefore important to understand as much as possible about how kidney stones form to improve both prevention and treatment. ...

Oncology & Cancer

Cancerous tumors: How likely are they to metastasize?

An aggressive type of cancer has provided a team of researchers supported by the Swiss National Science Foundation with an answer to the question of which tumor cells are at risk of spreading.

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