Psychology & Psychiatry

Protracted abstinence revisited

Opiate abuse is a chronic disorder and maintaining abstinence represents a major challenge for addicts.

Neuroscience

Prozac works better when used with other therapies

(Medical Xpress) -- The antidepressant fluoxetine, which is marketed under the name "Prozac," has been approved for use in the US for over two decades, and while some people find it effective, the results vary widely from ...

Neuroscience

How a popular antidepressant drug could rewire the brain

Prozac, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the medication exerts its mood-lifting ...

Psychology & Psychiatry

Antidepressant-suicide link in youths absent in new analysis

In 2004, concerns about antidepressant drugs increasing suicidal thoughts and behaviors in young patients prompted the FDA to issue a rare "black box warning." Now, a new analysis of clinical trial data finds that treatment ...

Medications

Antidepressants may raise risk for pregnancy complication

(HealthDay) -- Pregnant women taking the antidepressants known as selective serotonin reuptake inhibitors (SSRIs) face a slightly increased risk of developing dangerously high blood pressure, Canadian researchers report.

Psychology & Psychiatry

The far-reaching effects of antidepressants

When University of Ottawa biologists Marilyn Vera-Chang and Vance Trudeau began to study the effects of a popular antidepressant on reproduction levels in zebrafish, they stumbled across something that changed the course ...

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Fluoxetine

Fluoxetine (also known by the tradenames Prozac, Sarafem, Fontex) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is manufactured and marketed by Eli Lilly and Company. In combination with olanzapine it is known as Symbyax.

Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder.

Despite the availability of newer agents, fluoxetine remains extremely popular. In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States alone, making it the third most prescribed antidepressant after sertraline (SSRI; became generic in 2006) and citalopram (SSRI; became generic in 2003) in that country.

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