Genetics

Amount of mitochondrial DNA predicts frailty and mortality

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples' blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of ...

Diabetes

Frailty may up fracture risk in patients with type 2 diabetes

(HealthDay)—Patients with type 2 diabetes are frailer than participants without diabetes, and frailty increases the risk for fragility fractures, according to a study published in the April issue of Diabetes Care.

Health

Engaging in physical activity could reduce long-term mortality

Cognitive frailty is a heterogeneous clinical manifestation characterized by the simultaneous presence of both physical frailty and cognitive impairment, in the absence of dementia, and it seems to entail a greater death ...

Gerontology & Geriatrics

Increasing frailty may lead to death

A new study published in Age and Ageing indicates that frail patients in any age group are more likely to die than those who are not frail.

Diseases, Conditions, Syndromes

Frailty tied to liver transplant wait-list mortality in cirrhosis

(HealthDay)—In patients with cirrhosis, frailty is more frequently observed in those with ascites or hepatic encephalopathy (HE) and is independently associated with liver transplant wait-list mortality, according to a ...

Alzheimer's disease & dementia

Frailty could make people more susceptible to dementia

New research published in The Lancet Neurology journal suggests that frailty makes older adults more susceptible to Alzheimer's dementia, and moderates the effects of dementia-related brain changes on dementia symptoms. The ...

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Frailty

Frailty is a 2002 psychological thriller film directed by and starring Bill Paxton, and co-starring Matthew McConaughey. This film is the directorial debut for Paxton. The plot focuses on the strange relationship between two young boys and their father, who believes that he has been commanded by God to kill demons. The film was produced by David Kirschner.

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