Alzheimer's disease & dementia

Alzheimer's discovery reveals dire effect of toxic tau protein

Alzheimer's disease researchers at the University of Virginia have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding that could lead to new treatments.

Neuroscience

Overlooked tau-RNA interaction may play key role in dementia

Sometimes in science, "Eureka!" moments happen with surprisingly little effort. Sometimes they take years or decades to emerge. Such was the case with Brian Kraemer's research team and their recent study of the protein tau ...

Neuroscience

Targeting tau, the other protein behind Alzheimer's disease

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to ...

Medical research

Looking for an early sign of LATE: New insights into the pathology

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...

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