Medical research

Novel paradigm in drug development

Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...

Neuroscience

New method classifies brain cells based on electrical signals

For decades, neuroscientists have relied on a technique for reading out electrical "spikes" of brain activity in live, behaving subjects that tells them very little about the types of cells they are monitoring. In a new study, ...

HIV & AIDS

Heavy drinking and HIV don't mix

Heavy alcohol consumption (three drinks or more/day for women and four drinks or more/day for men) is linked to alterations in immune function among people with HIV.

Health

Nicotine-free e-cigarettes can damage blood vessels

Smoking e-cigarettes, also called vaping, has been marketed as a safe alternative to tobacco cigarettes and is rising in popularity among non-smoking adolescents. However, a single e-cigarette can be harmful to the body's ...

Diseases, Conditions, Syndromes

Painting a bigger biosociological picture of chronic pain

An integrated approach that unifies psychosocial factors with neurobiology sheds light on chronic pain traits and their underlying brain networks, according to a study published August 20 in the open-access journal PLOS Biology ...

Psychology & Psychiatry

Traumas change perception in the long term

People with maltreatment experiences in their childhood have a changed perception of social stimuli later as adults. This is what scientists from the Division of Medical Psychology at the University of Bonn have discovered. ...

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