Immunology

Research reveals how a fungal infection activates inflammation

Scientists at St. Jude Children's Research Hospital have identified the mechanisms behind inflammasome activation driven by infection with the fungal pathogen Aspergillus fumigatus. Fungal infection, especially with A. fumigatus, ...

Immunology

CRISPR reveals the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses. But our immune system ...

Diseases, Conditions, Syndromes

DNA sequencing and patient data used to halt infection outbreak

Clinical and research teams at Oxford University Hospitals (OUH) NHS Foundation Trust, using infection prevention and control best practice, whole genome sequencing and electronic patient data, have halted an outbreak of ...

Medical research

Protein unmasks pathogenic fungi to activate immune response

The first step in defending against a hostile attack is identifying the enemy. It's how a healthy immune system mounts a response to invading pathogens. In the case of certain fungi, however, the attacking cells may be so ...

Diseases, Conditions, Syndromes

Clostridium difficile infections may have a friend in fungi

The pathogen Clostridium difficile, which causes one of the most common hospital-acquired infections in the United States, may have accomplices that until now have gone largely unnoticed.

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