Genetics

Researchers discover new genes that fuse in cancer

Using new technologies that make it easier to sequence the human genome, researchers at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade ...

Oncology & Cancer

CRISPR catches out critical cancer changes

In the first large-scale analysis of cancer gene fusions, which result from the merging of two previously separate genes, researchers at the Wellcome Sanger Institute, EMBL-EBI, Open Targets, GSK and their collaborators have ...

Medical research

Making 'sense' of the 'cart before the horse' in mammalian cells

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome. ...

Oncology & Cancer

Gene fusion shifts cell activity into high gear, causing some cancer

The fusion of two adjacent genes can cause cancer by kicking mitochondria into overdrive and increasing the amount of fuel available for rampant cell growth, researchers at Columbia University Medical Center (CUMC) have discovered. ...

Medical research

One gene closer to regenerative therapy for muscular disorders

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature ...

Genetics

Team maps genomic landscape of schwannoma tumours

Researchers from the University Health Network (UHN); Toronto Western Neurosurgery Division and MacFeeters Hamilton Neuro-oncology Program at the Princess Margaret Cancer Centre have described the genomic landscape of schwannomas ...

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