Obstetrics & gynaecology

Some pregnant women are exposed to gadolinium in early pregnancy

A small but concerning number of women are exposed to a commonly used MRI contrast agent early in their pregnancy, likely before many of them are aware that they're pregnant, according to a study published in the journal ...

Radiology & Imaging

New contrast agent could make MRIs safer

Researchers at Massachusetts General Hospital (MGH) have taken a key step forward in developing a new, possibly safer contrast agent for use in magnetic resonance imaging (MRI) exams. Contrast enhanced MRI is a widely used ...

Radiology & Imaging

Artificial intelligence may help reduce gadolinium dose in MRI

Researchers are using artificial intelligence to reduce the dose of a contrast agent that may be left behind in the body after MRI exams, according to a study being presented today at the annual meeting of the Radiological ...

Medical research

Gadolinium deposition in the brain not dose dependent

Investigators at Children's Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the ...

Neuroscience

Eye could provide 'window to the brain' after stroke

Research into curious bright spots in the eyes on stroke patients' brain images could one day alter the way these individuals are assessed and treated. A team of scientists at the National Institutes of Health found that ...

page 1 from 2

Gadolinium

Gadolinium ( /ˌɡædɵˈlɪniəm/ gad-o-lin-ee-əm) is a chemical element with the symbol Gd and atomic number 64. It is a silvery-white, malleable and ductile rare-earth metal. It is found in nature only in combined (salt) form. Gadolinium was first detected spectroscopically in 1880 by de Marignac who separated its oxide and is credited with its discovery. It is named for gadolinite, one of the minerals in which it was found, in turn named for geologist Johan Gadolin. The metal was isolated by Lecoq de Boisbaudran in 1886.

Gadolinium metal possesses unusual metallurgic properties, with as little as 1% of gadolinium improving the workability and resistance of iron, chromium, and related alloys to high temperatures and oxidation. Gadolinium as a metal or salt has exceptionally high absorption of neutrons and therefore is used for shielding in neutron radiography and in nuclear reactors. Like most rare earths, gadolinium forms trivalent ions which have fluorescent properties. Gd (III) salts have therefore been used as green phosphors in various applications.

The Gd(III) ion occurring in water-soluble salts is quite toxic to mammals. However, chelated Gd(III) compounds are far less toxic because they carry Gd(III) through the kidneys and out of the body before the free ion can be released into tissue. Because of its paramagnetic properties, solutions of chelated organic gadolinium complexes are used as intravenously administered gadolinium-based MRI contrast agents in medical magnetic resonance imaging. However, in a small minority of patients with renal failure, at least four such agents have been associated with development of the rare nodular inflammatory disease nephrogenic systemic fibrosis. This is thought to be due to gadolinium ion itself, since Gd(III) carrier molecules associated with the disease differ.

This text uses material from Wikipedia, licensed under CC BY-SA