How do individual developing cells choose and commit to their "identity"—to become, for example, an immune cell, or a muscle cell, or a neuron?
Nov 19, 2018
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131
We're all born with a DNA sequence that encodes (in the form of genes) the very traits that make us, us—eye color, height, and even personality. We think of those genes as unchanging, but in reality, the way they are expressed, ...
Nov 8, 2018
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133
Unleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable outcomes in some cancer patients, but in many more, cancer cells evade the treatment and continue to spread. Now, ...
Nov 2, 2018
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64
In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these hormones have to bind to androgen ...
Jul 19, 2018
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4
A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers—about 17 percent—belong to a deadlier subtype of metastatic ...
Jul 9, 2018
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14
Two teams working independently of each other have found that it is possible to tease out gene expression patterns in tumor-infiltrating lymphocytes using single-cell RNA sequencing. The first team, based in Australia, sequenced ...
A fatty liver disease known as NASH—non-alcoholic steatohepatitis—is the nation's major cause of chronic liver disease, and is projected to become the most common indicator for liver transplants.
Jun 25, 2018
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11
Comparing regenerative tissue capabilities among animals is the focus of a new database created by a team of researchers at the University of Maine and MDI Biological Laboratory.
Jun 14, 2018
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0
From burning your palm on a hot pan handle to memorizing the name of a new acquaintance, "anytime you experience something, your neurons are active," says Kelsey Tyssowski, a graduate student in genetics at Harvard Medical ...
Apr 27, 2018
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2364
Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA ...
Apr 12, 2018
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