About 100 cancer predisposition genes (CPGs) are known. The probability of developing cancer is greater in individuals who inherit certain altered variants of one of these genes.
Jan 16, 2024
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Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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Gastric cancer, a significant global health burden, claims more than 7% of cancer-related deaths annually. Although only 1%–3% of cases have a genetic basis, understanding these genetic drivers is crucial for developing ...
Dec 27, 2023
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Tremendous progress has been made over the last decade in identifying genes leading to autism spectrum disorders (ASD), especially for those who are severely affected. To date, however, these genetic insights have not translated ...
Dec 18, 2023
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A study by researchers at Columbia and the Hong Kong University of Science and Technology is helping to clarify how low-grade lymphoma changes as it develops into a more aggressive tumor, which could lead to the development ...
Dec 18, 2023
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Gautam Dongre's two children in India and Pascazia Mazeze's son in Tanzania live with an inherited blood disorder that turns blood cells into instruments of pain.
Dec 14, 2023
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Researchers at the University of Tsukuba have demonstrated that in T follicular helper cell lymphoma, a subgroup of hematologic malignancies, individual tumor cells are highly heterogeneous, even within the same patient.
Dec 5, 2023
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Researchers at Fudan University and the Chinese Academy of Sciences, Shanghai, China, have conducted whole-brain genome editing targeted to correct a single-base mutation associated with autism spectrum disorder (ASD) in ...
Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new ...
Nov 16, 2023
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Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K.
Nov 16, 2023
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