News tagged with gene regulation

Related topics: genes · dna sequences · gene expression · genome · transcription factors

Screening the dark genome for disease

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine's understanding ...

Apr 03, 2017
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How diet influences our genes

What we eat can directly affect the genetic programs that regulate cellular function. A new EU project, coordinated by an LMU researcher, will explore how the products of metabolism intervene in gene regulation.

Apr 27, 2016
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Regulation of gene expression

Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.

Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.

Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.

Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.

This text uses material from Wikipedia, licensed under CC BY-SA

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