Scientists from the UCLA Jonsson Comprehensive Cancer Center have identified a key protein, transcription factor TAF12, that plays a critical role in the formation of a preinitiation complex, which consists of over one hundred ...
Jul 22, 2021
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Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...
Jul 20, 2021
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A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.
Jun 14, 2021
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Researchers at HSE University have identified the genes that play a crucial role in breast cancer metastasis. The results of the study were published in the journal PLOS ONE.
Apr 14, 2021
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Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study, published in Genome Biology, ...
Mar 29, 2021
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A large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a gene that plays a critical role in natural killer cell differentiation. In their paper published in the journal Science ...
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical ...
Feb 24, 2021
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A new study suggests that differences in the expression of gene transcripts—readouts copied from DNA that help maintain and build our cells—may hold the key to understanding how mental disorders with shared genetic risk ...
Feb 9, 2021
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Transcription factors—proteins that regulate gene expression—play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers. Understanding how transcription factors contribute ...
Feb 5, 2021
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How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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