Although visible signs of aging are usually unmistakable, unraveling what triggers them has been quite a challenge. Researchers at Baylor College of Medicine and collaborating institutions have discovered that a cellular ...
Aug 2, 2021
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809
Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...
Jul 20, 2021
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57
A large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a gene that plays a critical role in natural killer cell differentiation. In their paper published in the journal Science ...
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical ...
Feb 24, 2021
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How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms ...
Jan 19, 2021
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30
Genetics has made huge strides over the past 20 years, from the sequencing of the human genome to a growing understanding of factors that turn genes on and off, namely transcription factors and the DNA "enhancer" sequences ...
Dec 22, 2020
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Over two million babies, children, and adults in the United States are living with congenital heart disease—a range of birth defects affecting the heart's structure or function. Now, researchers at Gladstone Institutes ...
Dec 14, 2020
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50
Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...
Oct 1, 2020
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29
End-stage kidney disease often begins with injury to podocytes. These highly specialized cells are a critical part of the glomeruli, clusters of capillaries that serve as the filtration units in our kidneys' tightly-packed ...
Sep 7, 2020
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