Medical research

Increasing food intake by swapping mitochondrial genomes

Many of the characteristics that make people so different from each other are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation ...

Oncology & Cancer

'Junk DNA' affects inherited cancer risk

A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research published in the British Journal of Cancer ...

Immunology

Scientists identify genetic variation linked to severity of ALS

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two ...

Oncology & Cancer

DNA fracturing rewires gene control in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional ...

Genetics

Exploring the risk of ALL in children with Down syndrome

Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome. Historically, children with ...

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