Gene therapy may be the best hope for curing retinitis pigmentosa (RP), an inherited condition that usually leads to severe vision loss and blinds 1.5 million people worldwide.
Mar 21, 2024
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Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding ...
Mar 21, 2024
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An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led ...
Mar 21, 2024
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Researchers co-led by Nanyang Technological University, Singapore (NTU Singapore) and the University of Toulouse, France, have uncovered how bacteria and their toxins prompt the human immune response, leading to inflammation.
Mar 20, 2024
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Researchers from Karolinska Institutet, AstraZeneca, Würzburg University, Science for Life Laboratories and Uppsala University have found that oxidative stress in heart failure varies depending on sex, with female mouse ...
Mar 20, 2024
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A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form ...
Mar 20, 2024
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Around 98.5% of human DNA is non-coding, meaning it doesn't get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for how researchers can ...
Mar 19, 2024
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The middle-aged brain could provide a window into future cognitive health, researchers write in a review publishing March 19 in the journal Trends in Neurosciences. The team reviewed evidence from human and animal studies ...
Mar 19, 2024
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Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.
Mar 19, 2024
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The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
Mar 18, 2024
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