Cardiology

Tailoring treatment for preterm infants born with heart defects

The nonsteroidal anti-inflammatory drug indomethacin is routinely used to treat patent ductus arteriosus (PDA), a persistent opening between the aorta and pulmonary artery that is a common complication in preterm infants. ...

Neuroscience

Technique can image individual proteins within synapses

Our brains contain millions of synapses—the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such ...

Genetics

Exploring the risk of ALL in children with Down syndrome

Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome. Historically, children with ...

Genetics

Scientists hone in on DNA differences behind immune diseases

Scientists are one step closer to discovering the causes of immune diseases such as asthma, multiple sclerosis and arthritis. Research from the Wellcome Sanger Institute, GSK and Biogen, under the Open Targets initiative, ...

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