Genetics

New drugs more likely to be approved if backed up by genetics

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts. Emily King and colleagues ...

Diseases, Conditions, Syndromes

Calculating genetic links between diseases, without the genetic data

Physicians use standard disease classifications based on symptoms or location in the body to help make diagnoses. These classifications, called nosologies, can help doctors understand which diseases are closely related, and ...

Medical research

Increasing food intake by swapping mitochondrial genomes

Many of the characteristics that make people so different from each other are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation ...

Oncology & Cancer

'Junk DNA' affects inherited cancer risk

A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research published in the British Journal of Cancer ...

Genetic variation

Genetic variation, variation in alleles of genes, occurs both within and among populations. Genetic variation is important because it provides the “raw material” for natural selection.

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