Cambridge scientists have identified the cause of a rare, life-threatening form of hypoglycaemia. Their findings, which have the potential to lead to pharmaceutical treatments for the disorder, were published today in the ...
Oct 6, 2011
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St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome ...
May 4, 2015
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Zebrafish are an emerging power tool in cancer research. They can be engineered to light up when certain genes turn on—capturing the moment when a cancer is initiated. Because they breed so quickly, they lend themselves ...
Nov 1, 2018
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A specific genetic alteration has been discovered as a defining feature of epithelioid hemangioendothelioma (EHE), a rare but devastating vascular cancer. These findings have also been used to develop a new diagnostic test ...
Aug 31, 2011
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Using human kidney cells and brain tissue from adult mice, Johns Hopkins scientists have uncovered the sequence of steps that makes normally stable DNA undergo the crucial chemical changes implicated in cancers, psychiatric ...
Apr 14, 2011
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Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project – a sweeping, ...
Sep 5, 2012
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ALK rearrangement has been found in 9.6% of lung cancer patients tested in the Lung Cancer Mutation Consortium, and MET amplification in another 4.1%, reflecting how many patients might benefit from targeted therapies such ...
Jul 5, 2011
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Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a recently published study by researchers at McGovern Medical School at The University of ...
May 8, 2017
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(Medical Xpress) -- Two new studies have found that large structural abnormalities in chromosomes, some of which have been associated with increased risk of cancer, can be detected in a small fraction of people without a ...
May 8, 2012
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Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce ...
Feb 9, 2012
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