A gene that cured a man of HIV a decade ago has been successfully added to developing monkey embryos in an effort to study more potential treatments for the disease.
Nov 17, 2020
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St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome ...
May 4, 2015
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Cambridge scientists have identified the cause of a rare, life-threatening form of hypoglycaemia. Their findings, which have the potential to lead to pharmaceutical treatments for the disorder, were published today in the ...
Oct 6, 2011
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Zebrafish are an emerging power tool in cancer research. They can be engineered to light up when certain genes turn on—capturing the moment when a cancer is initiated. Because they breed so quickly, they lend themselves ...
Nov 1, 2018
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Using human kidney cells and brain tissue from adult mice, Johns Hopkins scientists have uncovered the sequence of steps that makes normally stable DNA undergo the crucial chemical changes implicated in cancers, psychiatric ...
Apr 14, 2011
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Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project – a sweeping, ...
Sep 5, 2012
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A specific genetic alteration has been discovered as a defining feature of epithelioid hemangioendothelioma (EHE), a rare but devastating vascular cancer. These findings have also been used to develop a new diagnostic test ...
Aug 31, 2011
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Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a recently published study by researchers at McGovern Medical School at The University of ...
May 8, 2017
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ALK rearrangement has been found in 9.6% of lung cancer patients tested in the Lung Cancer Mutation Consortium, and MET amplification in another 4.1%, reflecting how many patients might benefit from targeted therapies such ...
Jul 5, 2011
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(Medical Xpress) -- Two new studies have found that large structural abnormalities in chromosomes, some of which have been associated with increased risk of cancer, can be detected in a small fraction of people without a ...
May 8, 2012
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