Oncology & Cancer

Genetic alterations caused by cancer therapies identified

Living implies change. This is what happens to the cells of our bodies as we grow older: They accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain ...

Oncology & Cancer

Synthetic lethality offers a new approach to kill tumor cells

The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach ...

Diseases, Conditions, Syndromes

Genetics may explain severe flu in Chinese people

A genetic variant commonly found in Chinese people may help explain why some got seriously ill with swine flu, a discovery scientists say could help pinpoint why flu viruses hit some populations particularly hard and change ...

Oncology & Cancer

Synonymous genetic alterations: Not 'silent' at all

The so-called "silent" or "synonymous" genetic alterations do not result in altered proteins. But they can nevertheless influence numerous functions of the cell and thus also disease processes. Scientists from the German ...

Genetics

Genome sequencing of Burkitt Lymphoma reveals unique mutation

In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and ...

Oncology & Cancer

FDA approves personalized therapy for metastatic bladder cancer

(HealthDay)—The first personalized treatment for patients with metastatic bladder cancer and susceptible fibroblast growth factor receptor (FGFR) genetic alterations was granted accelerated approval by the U.S. Food and ...

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