Polygenic risk scores, which estimate a person's disease risk based on thousands or millions of common genetic variants, perform poorly in screening and prediction of common diseases such as heart disease, according to a ...
Oct 17, 2023
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A research team has identified a potential new drug for interstitial lung disease, a condition affecting approximately 4.7 million people worldwide, and validated its protective effects using patient-specific induced pluripotent ...
Oct 12, 2023
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A research team has discovered a microbial metabolite that destroys dopamine-producing neurons. Further experiments showed that Parkinson-like symptoms occur as a result.
Oct 11, 2023
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Research published in Nature provides new insight into human disease by studying how rare changes in genes affect proteins found in human blood, called plasma proteins. Findings revealed thousands of never-before-identified ...
Oct 9, 2023
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Dementia, which includes Alzheimer's disease, currently affects around 1.8 million people in Germany. The exact cause has not yet been clarified, but genetic factors play a significant role in the development of the disease. ...
Oct 6, 2023
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The discovery of eight new genes associated with a disease known as ossification of the posterior longitudinal ligament of the spine (OPLL) is a key step toward the development of effective treatments for this currently incurable ...
Oct 6, 2023
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When women with rheumatoid arthritis (RA) plan to become pregnant, many anguish over whether to stop their medications, risking a flareup in their disease, or continue with medication and risk possible harm to the baby.
Oct 5, 2023
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In an article revealed in Nature, scientists from deCODE Genetics, a subsidiary of the pharmaceutical company Amgen, demonstrated how plasma proteomics can contribute to a better understanding of diseases.
Oct 4, 2023
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Australian researchers at Walter and Eliza Hall Institute (WEHI) have found that a genetic change that increases the risk of inflammation, through a process described as "explosive" cell death, is carried by up to 3% of the ...
Oct 3, 2023
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Until recently, our understanding of Parkinson's disease has been quite limited, which has been apparent in the limited treatment options for management of this debilitating condition.
Oct 2, 2023
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