Health
E-cig vapor does not induce genetic mutations associated with cigarette smoke exposure
E-cigarette vapour does not induce DNA mutations commonly observed with tobacco smoke exposures in lab-based tests.
Nov 4, 2016
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143
News tagged with genetic instability
Oncology & Cancer
Hereditary factors that increase the likelihood of cancer mutations detailed in new study
Mutations occur in various tissues and organs of an individual. Somatic mutations occur in cells that will not give rise to offspring and are therefore not passed on to subsequent generations. Caused by a large number of ...
Jul 5, 2022
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294
Oncology & Cancer
Tumor 'signatures' could provide key to more accurate treatment for deadliest cancers
Scientists have found a way to identify and interpret 'signatures' that reveal the complex genetic causes of some of the deadliest cancers—which often have a survival rate of less than 10%. The results, published today ...
Jun 15, 2022
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52
Oncology & Cancer
Researchers identify possible approach to prevent cancer from evolving to resist treatment
A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. ...
Jan 26, 2023
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Oncology & Cancer
Loss of a DNA repair system creates a unique vulnerability in many cancer types
Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting ...
Apr 11, 2019
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100
Oncology & Cancer
Scientists show how BRCA1 cancer gene mutations harm breast cells
(Medical Xpress) -- Working with human breast cells, researchers at the Johns Hopkins Kimmel Cancer Center have shown how the inactivation of a single copy of the breast cancer gene BRCA1 leaves breast cells vulnerable to ...
Dec 14, 2011
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Oncology & Cancer
Researchers identify potential biomarker for cancer diagnosis
Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...
Jul 9, 2013
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Genetics
New biomarker links cancer progression to genome instability
Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and ...
Jan 10, 2019
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31
Oncology & Cancer
Scientists uncover the structure of a protein complex linked with breast and ovarian cancer risk
Scientists at the Francis Crick Institute have described the molecular structure of a key tumour suppressor protein and provided insights into its role in cells.
Jan 11, 2017
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9
Medications
Immunotherapy for bowel cancer could change clinical practice
A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of ...
May 29, 2020
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