Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and ...
Feb 7, 2013
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Oxidative stress damages DNA. Researchers in the Vetsuisse Faculty have now decoded the mechanism that repairs DNA damaged in this way. This repair mechanism could lead to less invasive approaches in cancer therapy and contribute ...
Dec 27, 2011
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A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...
Mar 1, 2013
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Lung adenocarcinomas in people who have never smoked show greater genome instability than those in smokers, supporting the theory that lung cancer in never smokers arises through different pathways, according to research ...
Jul 5, 2011
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Fanconi anemia is a rare genetic disease characterized by hematologic symptoms that include low platelet count and unusually large red blood cells. Mutations in nearly 20 genes have been identified as causative for Fanconi ...
Jul 10, 2017
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(Medical Xpress) -- A study by researchers at UC Davis has found that pregnant women with a particular gene variation are more likely to produce auto-antibodies to the brains of their developing fetuses and that the children ...
Oct 19, 2011
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How can defective gene activity leading to cancerbe avoided? Researchers at the University of Zurich have now identified a mechanism by which cells pass on the regulation of genetic information through epigenetic modifications. ...
Oct 30, 2017
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A new study led by Yale School of Medicine scientists has pinpointed why some adults—by some estimates, at least 50% of the population after 75 years of age—develop hearing problems.
May 16, 2023
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One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies.
Oct 15, 2012
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Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in ...
Apr 23, 2013
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