Medical research

A new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research (CNIC) led by Rui Benedito have developed a new genetic tool called iSuRe-Cre that provides certainty in Cre-inducible genetic modifications, a key technique for ...

Neuroscience

Does our environment affect the genes in our brains?

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers from Charité - Universitätsmedizin Berlin have shown that modifications in the structure of a specific gene have ...

Genetics

Important mechanism of epigenetic gene regulation identified

How can defective gene activity leading to cancerbe avoided? Researchers at the University of Zurich have now identified a mechanism by which cells pass on the regulation of genetic information through epigenetic modifications. ...

Genetics

Mysterious DNA modification seen in stress response

With advances in genomics, scientists are discovering additional components of the DNA alphabet in animals. Do these unusual chemical modifications of DNA have a special meaning, or are they just signs that cellular machines ...

Diseases, Conditions, Syndromes

Promising results for two genetic weapons against malaria

Two new papers by researchers at the Johns Hopkins Bloomberg School of Public Health's Malaria Research Institute report successes for highly promising strategies against malaria, a disease that still kills more than 400,000 ...

Diseases, Conditions, Syndromes

Americans OK with GMs for health care, but still wary about food

More than three-quarters of Americans would accept release of genetically modified mosquitoes to decrease risk of the Zika virus, but fewer than half accept genetic modification (GM) of animals, grain crops and produce, according ...

Genetics

Mom's smoking alters fetal DNA

A study of over 6,000 mothers and their newborn children—one of the largest studies of its kind—solidifies the evidence that smoking cigarettes while pregnant chemically modifies a fetus' DNA, mirroring patterns seen ...

Medical research

Scientists unlock genetic secret that could help fight malaria

A group of scientists, including one from the University of California, Riverside, have discovered a long-hypothesized male determining gene in the mosquito species that carries malaria, laying the groundwork for the development ...

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Genetic engineering

Genetic engineering, recombinant DNA technology, genetic modification/manipulation (GM) and gene splicing are terms that apply to the direct manipulation of an organism's genes. Genetic engineering is different from traditional breeding, where the organism's genes are manipulated indirectly. Genetic engineering uses the techniques of molecular cloning and transformation to alter the structure and characteristics of genes directly. Genetic engineering techniques have found some successes in numerous applications. Some examples are in improving crop technology, the manufacture of synthetic human insulin through the use of modified bacteria, the manufacture of erythropoietin in hamster ovary cells, and the production of new types of experimental mice such as the oncomouse (cancer mouse) for research.

The term "genetic engineering" was coined in Jack Williamson's science fiction novel Dragon's Island, published in 1951, two years before James Watson and Francis Crick showed that DNA could be the medium of transmission of genetic information.

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