Oncology & Cancer

Research team discovers new target for CAR T cells in solid tumors

Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...

Neuroscience

Touch sensitive brain cells controlled by micromagnets

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of ...

Diseases, Conditions, Syndromes

RNA modification may protect against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from ...

Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

Oncology & Cancer

A leap forward in research on CAR T cell therapy

In cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of the most significant recent advances in immunotherapies targeted at cancer.

Genetics

Mysterious DNA modification seen in stress response

With advances in genomics, scientists are discovering additional components of the DNA alphabet in animals. Do these unusual chemical modifications of DNA have a special meaning, or are they just signs that cellular machines ...

Diseases, Conditions, Syndromes

Promising results for two genetic weapons against malaria

Two new papers by researchers at the Johns Hopkins Bloomberg School of Public Health's Malaria Research Institute report successes for highly promising strategies against malaria, a disease that still kills more than 400,000 ...

Genetics

Mom's smoking alters fetal DNA

A study of over 6,000 mothers and their newborn children—one of the largest studies of its kind—solidifies the evidence that smoking cigarettes while pregnant chemically modifies a fetus' DNA, mirroring patterns seen ...

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