Oncology & Cancer

Notorious cancer protein mutations cooperate to proliferate disease

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious ...

Alzheimer's disease & dementia

Genetic changes implicated in altered Alzheimer's risk

Today, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is also involved in the more common form of the condition. They also suggest genes that ...

Genetics

When your microbiome and your genome aren't a good combination

One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being. In addition to extracting nutrients from food, the collective activity of these tiny organisms ...

Medications

Epilepsy drug inhibits brain tumor development

Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...

Medical research

Scientists identify a genetic basis for healthy sleep

From organisms as simple as worms to those as complex as humans, sleep is a fundamental necessity. But although an estimated 50 to 70 million people in the United States suffer from a chronic sleep disorder, the genetic mechanisms ...

Neuroscience

Study reveals how glial cells may play key epilepsy role

A new study provides potential new targets for treating epilepsy and new fundamental insights into the relationship between neurons and their glial "helper" cells. In eLife, scientists at MIT's Picower Institute for Learning ...

Oncology & Cancer

How a common oral bacteria makes colon cancer more deadly

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum—a common oral bacteria often implicated in tooth decay—accelerates the growth of colon cancer. The study was published ...

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