Oncology & Cancer

Researchers identify genes behind uterine leiomyosarcoma

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS). Furthermore, using fully sequenced patient-derived xenografts, the team has preclinically validated new ...

Oncology & Cancer

Stomach-specific c-Myc overexpression and gastric cancer

Gastric cancer is one of the most common malignant cancers worldwide. Since the stage of early gastric cancer usually lasts for a long time and lacks obvious symptoms, the diagnosis of early gastric cancer is very difficult. ...

Oncology & Cancer

New computational method detects disrupted pathways in cancer

Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, ...

Oncology & Cancer

Errant DNA boosts immunotherapy effectiveness

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate. The findings, published online ...

Psychology & Psychiatry

Uncovering genetic roots of marijuana use disorder

A large study exploring possible genetic influences on cannabis use disorder has identified two regions in our DNA—one newly identified and a second that replicates a past finding—that appear to contribute to one's risk ...

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