Cancer often picks up genetic changes that allow it to resist treatment. But this takes time. How do cancer cells undergoing drug treatment survive long enough to evolve? To answer this question, a study presented at the ...
Apr 16, 2018
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Targeted treatments have revolutionized care for lung cancer patients whose tumors harbor ALK or ROS1 alterations. Basically, cancers may use these genetic changes to drive their growth, but also become dependent on the action ...
Apr 11, 2018
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The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States. However, many patients have tumors ...
Oct 17, 2017
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Novel molecular tests are gaining popularity as a rapid way to detect genetic mutations that render tuberculosis impervious to drugs. Yet, how well these new tests fare in gauging risk of actual drug failure and patient death ...
Aug 3, 2017
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Antibiotics are lifesaving drugs, but overuse is leading to one of the world's most pressing health threats: antibiotic resistance. Researchers at the University of Rochester Medical Center are developing a tool to help physicians ...
Jul 28, 2017
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A form of genetic variation, called differential RNA splicing, may have a role in tumor aggressiveness and drug resistance in African American men with prostate cancer. Researchers at the George Washington University (GW) ...
Jun 30, 2017
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The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought. Analysis of 355 biopsied tumors from patients who acquired resistance to EGFR ...
Mar 16, 2017
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A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine today (Monday).
Nov 21, 2016
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A large-scale genetic study has provided strong evidence that the development of insulin resistance - a risk factor for type 2 diabetes and heart attacks and one of the key adverse consequences of obesity - results from the ...
Nov 14, 2016
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Scientists at the Wellcome Trust Sanger Institute and their collaborators have discovered genetic markers in malaria parasites linked with resistance to the anti-malarial drug piperaquine. Reported in Lancet Infectious Diseases, ...
Nov 3, 2016
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