Health informatics

Bioinformatics: At the forefront, behind the scenes

Bioinformatics is an inherently interdisciplinary effort, combining the molecular biology revolution heralded by pioneers like Watson and Crick with advances in computer science that have placed previously unimaginable abilities ...

Genetics

New mutations accumulate in reproductive cells of older mice

Older mice have more new mutations—changes in DNA sequence that occur in the individual rather than being inherited from a parent—than younger mice in the genomes of their mitochondria, according to researchers at Penn ...

Genetics

New genomic atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in ...

Genetics

Genomes front and center of rare disease diagnosis

A research program pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease. Whole genome sequencing is the technology used by the 100,000 Genomes ...

page 1 from 47