Diseases, Conditions, Syndromes

Study shows glucagon is key for kidney health

Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers removed receptors for this hormone ...

Medical research

A single, master switch for sugar levels?

A single neuron appears to monitor and control sugar levels in the fly body, according to research published this week in Nature. This new insight into the mechanisms in the fly brain that maintain a balance of two key hormones ...

Diabetes

Diabetes' sworn enemy could ultimately be a valuable ally

When people talk about diabetes, they usually also talk about insulin. Diabetes is a disease that affects millions of people around the world; insulin is a hormone that helps control this disease. Now a third term could soon ...

Medical research

Human cells can also change jobs

Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. By inducing non-insulin-producing human pancreatic cells to modify their function to produce insulin in ...

Diabetes

Our bodies may cure themselves of diabetes in the future

Diabetes is the inability to produce insulin, a hormone that regulates blood sugar levels, due to damaged or non-existing insulin cells. Many diabetes patients take insulin supplements to regulate these levels.

Medical research

Research opens the door to improved drugs for type 2 diabetes

Type 2 diabetes, a prolific killer, is on a steep ascent. According to the World Health Organization, the incidence of the condition has grown dramatically from 108 million cases in 1980 to well over 400 million today. The ...

Medical research

High insulin levels tied to obesity pathway, research shows

UT Southwestern Medical Center researchers have identified a crucial link between high levels of insulin and pathways that lead to obesity, a finding that may have important implications when treating diabetes.

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Glucagon

Glucagon, a hormone secreted by the pancreas, raises blood glucose levels. Its effect is opposite that of insulin, which lowers blood glucose levels. The pancreas releases glucagon when blood sugar (glucose) levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. High blood glucose levels stimulate the release of insulin. Insulin allows glucose to be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels at a stable level. Glucagon belongs to a family of several other related hormones.

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