Immunology

How sugar promotes inflammation

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease. In affected patients, the immune system attacks the body's own tissue and the ...

Medical research

How important is the gut microbiome? It may depend on your genetics

Our gut microbiomes—the bacteria that live in our digestive tract—play major roles in our health. Scientists around the world are studying therapies that manipulate the microbiome, including probiotics (such as live bacterial ...

Medical research

Artificial sweeteners linked to abnormal glucose metabolism

Artificial sweeteners, promoted as aids to weight loss and diabetes prevention, could actually hasten the development of glucose intolerance and metabolic disease; and they do it in a surprising way: by changing the composition ...

Oncology & Cancer

Lung cancer resistance: the key is glucose

Cancers are not only made of tumor cells. In fact, as they grow, they develop an entire cellular ecosystem within and around them. This "tumor microenvironment" is made up of multiple cell types, including cells of the immune ...

Medical research

Gut microbes trigger fat loss in response to cold temperatures

Exposure to cold temperatures is known to mimic the effects of exercise, protecting against obesity and improving metabolic health. A study published December 3 in Cell now reveals that the beneficial health effects of cold ...

Oncology & Cancer

Fundamental cancer metabolism dogma revisited

A new paper in Nature Communications reveals new insights into adaptations made by cancer cells to rewire their metabolism to achieve growth and survive. Among the discoveries include a challenge to a well-known feature in ...

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