Oncology & Cancer

Researchers identify a mechanism that fuels cancer cells' growth

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes ...

Diabetes

A novel insulin accelerant

Insulin levels rise after eating a meal, signaling uptake of circulating glucose by skeletal muscle. In individuals with diabetes this process is often impaired—a condition known as insulin resistance.

Oncology & Cancer

How obesity drives colon cancer in mice

Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, ...

Diabetes

Culprit in reducing effectiveness of insulin identified

Scientists at Osaka University have discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduces the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake.

Medical research

Secrets of longevity protein revealed in new study

Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent Yale-led study, researchers revealed the three-dimensional structure ...

Health

HIIT alters brain glucose metabolism in insulin resistant people

Researchers at the University of Turku, Finland, studied how high-intensity interval training (HIIT) alters the brain's glucose metabolism in physically inactive insulin resistant people. Only two weeks of HIIT training reduced ...

Medical research

Is Alzheimer's disease a disorder of energy metabolism?

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset ...

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