A research group at Nagoya University in Japan has discovered a new treatment for type 1 diabetes that uses leptin, a hormone secreted by fat cells. Treating mice models of insulin-dependent diabetes mellitus (a condition ...
Sep 14, 2022
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Progressive dysfunction and failure of insulin-releasing β-cells is a hallmark of type 2 diabetes (T2D). DZD researchers have now shown that diabetes-resistant and diabetes-susceptible mice respond differently to a carbohydrate-rich ...
Aug 31, 2022
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Most drugs developed to treat Alzheimer's disease have for years been ineffective in clinical trials. Researchers from Indiana University School of Medicine recently evaluated the efficacy of a failed clinical trial drug ...
Jul 25, 2022
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Type 2 diabetes is a major public health problem that affects millions of people worldwide. Developing new drugs to help better treat its underlying causes is therefore a research priority. In a new study coordinated by Inserm ...
Jul 13, 2022
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Drug-induced parkinsonism is not well understood. Chronic use of flunarizine (FNZ), a drug often used for treating dizziness, migraine, epilepsy, and peripheral vascular diseases, may induce parkinsonism. Previous investigations ...
Apr 21, 2022
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A new paper in Nature Communications reveals new insights into adaptations made by cancer cells to rewire their metabolism to achieve growth and survive. Among the discoveries include a challenge to a well-known feature in ...
Mar 23, 2022
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Infection with respiratory syncytial virus during infancy results in metabolic reprogramming of epithelial cells lining the airway, according to a Northwestern Medicine study published in the journal Viruses.
Nov 22, 2021
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A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine ...
Apr 22, 2021
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In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. ...
Feb 1, 2021
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Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows. The findings, reported in a recent issue ...
Jul 23, 2020
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