Medical research

To assess a cell's health, follow the glucose

A new spectroscopic technique reveals that glucose use in live cells provides valuable information about the functional status of cells, tissues, and organs. Shifts in a cell's use of glucose can signal changes in health ...

Oncology & Cancer

Researchers identify a mechanism that fuels cancer cells' growth

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes ...

Oncology & Cancer

How obesity drives colon cancer in mice

Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, ...

Medical research

Secrets of longevity protein revealed in new study

Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent Yale-led study, researchers revealed the three-dimensional structure ...

Medical research

High-fat diet starves the brain

A high-fat diet of three days in mice leads to a reduction in the amount of glucose that reaches the brain. This finding was reported by a Research Group led by Jens BrĂ¼ning, Director at the Max Planck Institute for Metabolism ...

Alzheimer's disease & dementia

Low sugar uptake in brain appears to exacerbate Alzheimer's disease

A deficiency in the protein responsible for moving glucose across the brain's protective blood-brain barrier appears to intensify the neurodegenerative effects of Alzheimer's disease, according to a new mouse study from the ...

Oncology & Cancer

Role for sugar uptake in breast cancer revealed

Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, Mina Bissell, Distinguished Scientist with Berkeley Lab's Life Sciences Division and a leading ...

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