Neuroscience

Scientists capture first image of major brain receptor in action

Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, ...

Neuroscience

Scientists chart how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic ...

Alzheimer's disease & dementia

New drug target for Alzheimer's, stroke discovered

A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative ...

Medical research

Researchers unravel molecular roots of Down syndrome

Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain.

Medical research

Study explores potential new class of antidepressants

Researchers at Vanderbilt University Medical Center have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer ...

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